Murray and Patrick are the matchup picks, but Davis and Waddle are the talent picks. Taking one from each group limits your downside, and gives you some upside. Since two of them are in the same game (Patrick and Davis), I’d only pick one from there, and Davis would be the pick since the Jets should have a pass heavy game plan.
For Murray or Waddle, I lean towards Murray, only because it’s Detroit, and it’s not a PPR league.
I am completely ignoring Sermon until he proves he is the 49ers main back.