You have the right idea already. Stafford and Wilson are neck-and-neck in the projections I looked at. I would lean towards Stafford just on his talent and the overall talent of the Rams offense.
Tough one. If you are behind in projections, you need to bring a riskier lineup.
Stafford has the better matchup. Bills - Rams has been a shootout before, and the over/under is significantly higher than for the Broncos - Seahawks game.
However, if it is a high-scoring game, chances are Kupp will benefit heavily as well. And I don’t know if starting Stafford as a security blanket will be enough to give you a W.
If you are behind in projections, I would probably chose the riskier option here and hope that the Broncos will score more than the Rams. And start the combo of Russell and Sutton. Yes, there is a high risk this will backfire, but unless your opponent has no other assets aside of Kupp, you will probably have to take that risk.
I would also start Aiyuk, hoping that the grapevine rumors are correct and he is the new WR1 in San Francisco.
Hope you went with Wilson in the revenge game. Then JT and Chase E. Also JJ and Sutton. Flex I like CEH. He needs to prove he’s the guy, and I think Patrick trusts him with the check downs. Bateman and Hall are both good but, I need to see something there first. Good luck.